Aman Makaju

Aman Makaju is a senior scientist in the Discovery Proteomics Group at Amgen Research and Development.

In his current capacity, he plays a crucial role in supporting Amgen’s Drug Discovery pipeline through the application of mass spectrometry-based proteomics. Aman is an integral part of a dynamic team that has successfully developed a cutting-edge, high-throughput mass spectrometry-based proteomics platform.

This platform has been designed to expedite the discovery process of induced protein proximity modalities, with a particular emphasis on identifying and characterizing molecular glues for targeted protein degradation. The platform's capabilities include the untargeted identification of glue-induced protein-protein interactions, tracking on- and off-target protein degradation events, and monitoring the ubiquitination of target proteins.